{"id":2647,"date":"2026-04-14T20:53:38","date_gmt":"2026-04-14T20:53:38","guid":{"rendered":"https:\/\/dr-yaser.com\/?p=2647"},"modified":"2026-04-14T20:56:44","modified_gmt":"2026-04-14T20:56:44","slug":"%d8%a7%d9%84%d8%b7%d9%81%d9%84-%d8%a7%d9%84%d9%85%d8%b5%d8%a7%d8%a8-%d8%a8%d8%a7%d9%84%d8%b3%d8%b9%d8%a7%d9%84-2","status":"publish","type":"post","link":"https:\/\/dr-yaser.com\/?p=2647&lang=en","title":{"rendered":"Antihistamines"},"content":{"rendered":"<div data-diff-type=\"normal\" data-diff-line=\"6\">\n<div style=\"text-align: justify;\">\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\"><strong>What is Histamine?<\/strong><\/span><br \/>\n<span style=\"font-size: 14pt;\">Histamine is a protein used by the immune system to help protect the body&#8217;s cells from infection. If the immune system detects a harmful foreign organism, such as bacteria or a virus, histamine is released into nearby cells. Histamine causes small blood vessels to dilate and the surrounding skin to swell, a condition known as inflammation.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\"><strong>Why should I take antihistamines?<\/strong><\/span><br \/>\n<span style=\"font-size: 14pt;\">You can take antihistamines if you have allergy symptoms, such as hay fever, allergic skin rash, and skin itching. Some antihistamines block histamine receptors in the brain. They can be very beneficial for treating travel fatigue, dizziness, or nausea related to migraines.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\"><strong>What are the main types of antihistamines?<\/strong><\/span><br \/>\n<span style=\"font-size: 14pt;\">There are two types of antihistamines: sedating and non-sedating.<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\"><strong>Sedating Antihistamines:<\/strong>\u00a0They work in the brain as well as the rest of the body, and can cause drowsiness. Examples include Chlorphenamine, Loratadine, or Cetirizine.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\"><strong>Non-sedating Antihistamines:<\/strong>\u00a0They do not easily cross into the brain, so they do not cause drowsiness, meaning they do not relieve fatigue. This type includes medications such as Cetirizine and Desloratadine.<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\"><strong>Which type of antihistamine should be used?<\/strong><\/span><br \/>\n<span style=\"font-size: 14pt;\">Second-generation antihistamines are generally recommended, although sometimes and in certain circumstances they may cause drowsiness similar to that caused by first-generation antihistamines. For example, if you have trouble sleeping because of itchy skin.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\"><strong>What forms are antihistamines available in?<\/strong><\/span><br \/>\n<span style=\"font-size: 14pt;\">Antihistamines are available as tablets, creams, or nasal sprays.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\"><strong>What are the main indications for using an antihistamine?<\/strong><\/span><br \/>\n<span style=\"font-size: 14pt;\">Allergic conditions that can benefit and improve from the use of antihistamines include:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Allergic Rhinitis<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Atopic eczema<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Urticaria (hives)<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Allergic Conjunctivitis<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Allergic reactions resulting from insect bites and stings<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Allergic reactions to certain types of foods and drinks<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\"><strong>Can I take antihistamines during pregnancy?<\/strong><\/span><br \/>\n<span style=\"font-size: 14pt;\">As a general rule, no medication should be taken during pregnancy unless there is a clear medical need. You should always check with your doctor before taking any medication. If your doctor believes there is a need to take them, the antihistamines considered safest during pregnancy are Chlorphenamine and Loratadine. Short-term medical trials suggest that Chlorphenamine is suitable for use during pregnancy. They should be prescribed only when absolutely necessary and avoided in the first trimester of pregnancy.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\"><strong>Who should not take antihistamines?<\/strong><\/span><br \/>\n<span style=\"font-size: 14pt;\">Caution should be exercised when using sedating antihistamines in the following cases:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Benign Prostatic Hyperplasia and Urinary Retention<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Acute Glaucoma<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Epilepsy: Precautions should be taken when using it.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Hepatic &amp; Renal Impairment<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\"><strong>What are the main side effects of antihistamines?<\/strong><\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Sedation: This is one of the problems associated with first-generation antihistamines, although it may also affect some patients taking second-generation ones.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Dizziness tends to disappear over time.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span style=\"font-size: 14pt;\">Less common side effects include: blurred vision, difficulty urinating, dry mouth, vomiting, constipation or diarrhea, skin or eye irritation (from preparations, creams, and eye drops).<\/span><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>What is Histamine?<br \/>\nHistamine is a protein used by the immune system to help protect the body&#8217;s cells from infection. If the immune system detects a harmful foreign organism, such as bacteria or a virus, histamine is released into nearby cells. Histamine causes small blood vessels to dilate and the surrounding skin to swell, a condition known as inflammation.<\/p>\n","protected":false},"author":1,"featured_media":2743,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[66],"tags":[],"class_list":["post-2647","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-allergy-medications"],"jetpack_featured_media_url":"https:\/\/dr-yaser.com\/wp-content\/uploads\/2026\/04\/Histamine.jpg","_links":{"self":[{"href":"https:\/\/dr-yaser.com\/index.php?rest_route=\/wp\/v2\/posts\/2647","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dr-yaser.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dr-yaser.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dr-yaser.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dr-yaser.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2647"}],"version-history":[{"count":4,"href":"https:\/\/dr-yaser.com\/index.php?rest_route=\/wp\/v2\/posts\/2647\/revisions"}],"predecessor-version":[{"id":2747,"href":"https:\/\/dr-yaser.com\/index.php?rest_route=\/wp\/v2\/posts\/2647\/revisions\/2747"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dr-yaser.com\/index.php?rest_route=\/wp\/v2\/media\/2743"}],"wp:attachment":[{"href":"https:\/\/dr-yaser.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2647"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dr-yaser.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2647"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dr-yaser.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2647"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}